The DISOPRED2 Prediction of Protein Disorder Server

Dynamically disordered protein chains do not have stable secondary structures and have high flexibility in solution. Disordered regions also play critical roles in protein function. A description of DISOPRED2 and the relevance of disorder in protein function can be found here.

 

Input Sequence (single letter amino acid code)


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If you wish to test these services follow this link to retrieve a test fasta sequence.
 

Prediction Options

False Positive Threshold:
Include PSIPRED secondary structure prediction
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Output Options

Don't return PSI-BLAST output
Return PSI-BLAST hits only
Return PSI-BLAST hits and alignments
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Warning: PSI-BLAST can produce very large output files - please be sure you are able to receive very long e-mail messages if you use these options.
 

Submit Sequence

Email Address for job completion alert (optional)

Short identifier for submission

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Acceptable Use Policy

This server is run on a strictly best-efforts basis. We aim the service primarily at biologists trying to analyse their own sequences, as such the service is designed for users who submit small numbers of jobs to the queue in any given day.

We recognise that increasingly there are projects that need more substantial access to the server, but our current web servers have only limited capacity.

If we find that users are abusing the good faith of the service then their site access may be restricted or in extreme cases blocked completely. We hope such cases will be rare and we will only resort to blocking sites if repeat usage is severely interfering with the service for other users.

Since October 2010, users may submit unlimited jobs to the queue per day but users are limited to not more than 10 concurrent jobs. All results will remain available on our server for 30 days after which time they will be deleted. If you need high-priority or high-capacity access to our server then please contact us to discuss purchasing dedicated server capacity or the possibility of collaboration. For instance, if you are running a genomics project or meta-server that needs to submit hundreds of jobs per day to our server then we can now offer this capacity at cost. You remain welcome to make use of the free service, but only at the default low priority.

Data Protection

We do not reuiqre that users submit email addresses but users may find it useful to provide one in order to receive email alerts when their jobs complete. Email addresses submitted to our web site are used to return analysis results. We also use email addresses to track user's server usage and we may use them to contact users should any problems that may arise as a result of their data submissions. We will not use your email address for any other purpose or pass them on to third parties

Intellectual Property Disclaimer

All data submitted to this web service is made publicly accessible, and we do not guarantee confidentiality. This may affect your ability to seek intellectual property protection for your data. If you do not wish to publicly disclose your data you may either download our software or you can contact us to discuss the possibility of a collaboration

Commercial Use Enquiries

This server is available for commercial use. However all results generated are publicly accessible. If you wish to have secure private access or you wish to licence the relevant software please contact Ebisu. They can provide a very quick response to any commercial enquiries regarding access to our web servers, software, databases or bioinformatics consultancy services.

Current Contributors

David T. Jones, Kevin Bryson & Daniel Buchan

Previous Contributors

Liam J. McGuffin


Ward JJ, Sodhi JS, McGuffin LJ, Buxton BF and Jones DT (2004)
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
Journal of Molecular Biology, 337, 635-645.


this is my tip title
and we can even put more in here if we wish.